The overall winner of the Designs of the Year 2015 have been announcd by the Design Museum, across architecture, digital, fashion, graphics, product and transport.

Known as human-organs-on-chips, these microdevices are lined with human cells and mimic the design and function of human organs perfectly.

They were designed by Donald Ingber and Dan Dongeun, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University.

"Each Organ-on-a-Chip models natural tissue structures and mirrors the dynamic mechanical behavior of internal organs." says its creators. "Chips can also can be linked to form a ‘Human Body-on-Chips’, which can be analysed to learn how drugs impact each organ as they are distributed and metabolized throughout the body.

"Cells from individual patients or from genetically-related populations can be used to inhabit these Organs-on-Chips to build mimics of their organs, a tactic that promises to advance personalized medicine, accelerate drug discovery and decrease development costs.

Read on to see our pick of this year's category winners and nominees – which are on show in the Museum on the bank of the Thames in London until March 31 2015 - and to discover what trends connect them.

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